About Us

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Our Mission

Whole Genome Sciences exists to advance scientific understanding of the complete human genome and to translate this knowledge into improved diagnosis, treatment, and prevention of genetic disease.

We focus on the genomic regions that remain largely uncharacterized in clinical medicine — including regulatory, splicing, and other non-coding elements — where the majority of pathogenic variation resides.

Our work is guided by scientific rigor, transparency, and a commitment to improving human health through foundational genomic research.

Research Use and Data Stewardship

Whole Genome Sciences is a nonprofit research organization dedicated to advancing public-benefit genomics and precision medicine through open, ethically governed, and publishable scientific research.

WGS conducts non-commercial research using large-scale genomic and clinical datasets to study the genetic and molecular mechanisms underlying human disease, with a particular focus on noncoding regulatory and splicing variation.

We are committed to responsible data stewardship, ensuring that genomic data generated through our research initiatives is managed in accordance with the highest ethical standards and regulatory requirements.Research conducted by WGS is intended for peer-reviewed publication and broad scientific dissemination. WGS does not engage in the resale of data, participant re-identification, or proprietary exploitation of controlled-access research datasets.

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Scientific Focus Areas

Whole Genome Sciences conducts and supports research in:

  • Functional annotation of the non-coding genome
  • Regulatory and splicing element discovery
  • Computational genomics and algorithm development
  • Whole-genome interpretation beyond exome sequencing
  • Genetic mechanisms underlying rare, undiagnosed, and common diseases

Our efforts are designed to complement and extend existing genomic research initiatives, addressing critical blind spots in current clinical and research pipelines.

Founder

Whole Genome Sciences was founded by Dr. Periannan Senapathy, a computational genomics researcher whose work has focused on gene structure, splice-site recognition, and the architecture of the non-coding genome. Dr. Senapathy has contributed to statistical and computational approaches for understanding exon–intron organization and regulatory elements in eukaryotic genomes. His research interests include the origins of genomic architecture and the role of non-coding variation in human disease.

He established Whole Genome Sciences to support independent, publication-driven research advancing foundational genomic knowledge for the public benefit.

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© Whole Genome Sciences • 501(c)(3) Public Charity • EIN 41-3785977

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